17 articles - From Saturday Mar 26 2022 to Friday Apr 01 2022
Guidelines, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Am J Clin Nutr |
Gut microbiota-derived metabolite Trimethylamine-N-oxide (TMAO) and multiple health outcomes: an umbrella review and updated meta-analysis. TMAO might be a novel biomarker related to human health conditions including all-cause mortality, hypertension, cardiovascular disease, diabetes, cancer and kidney function. Further studies are needed to investigate whether circulating TMAO levels could be an intervention target for chronic disease. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
Changes in circulating MicroRNAs-99/100 and reductions of visceral and ectopic fat depots in response to lifestyle interventions: the CENTRAL trial. Decreases in circulating miR-99-5p/100-5p levels induced by lifestyle interventions were related to improved body fat distribution and ectopic fat accumulation. Our study suggests that changes in circulating adipose-related miR-99-5p/100-5p may be linked to reducing diabetogenic fat depots in patients with abdominal obesity. |
Ultra-processed food consumption and kidney function decline in a population-based cohort in the Netherlands. Higher UPF consumption was associated with a higher risk of a composite kidney outcome (incident CKD or = 30% eGFR decline) and a more rapid eGFR decline in the general population, independent of confounders and other dietary indices. |
| Liver Transpl |
A look into hemostatic characteristics during pediatric liver transplantation using the thromboelastometry (ROTEM® ) test. In children undergoing LT, coagulation profiles depend on the etiology for LT. During LT, ROTEM ® parameters could help detect thrombocytopenia and hypofibrinogenemia and guide transfusion therapy as a point of care monitoring method. |
Cirrhotic Cardiomyopathy: Appraisal of the Original and Revised Criteria in Predicting Post-Transplant Cardiac Outcomes. CCM, only when defined by the revised criteria, was associated with increased risk for MACE after LT, validating the recently revised CCM definition. Abnormal septal e', reflecting impaired relaxation, appears to be the most predictive echocardiographic criterion for MACE after LT. |
Donation After Circulatory Death Transplant Outcomes Utilizing Livers Recovered by Local Surgeons. One-year graft survival was 91.5% for TPT grafts and 95.5% for NTPT grafts. Excellent outcomes can be achieved using NTPT for recovery of DCD livers. There may be an opportunity to expand utilization of DCD livers in the United States by increasing utilization of NTPT. |
| Pancreatology |
Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms. A shared causal CTRC risk variant might unfold its pathogenic effect in ACP and NACP by reducing CTRC expression, while the CLDN2-MORC4 shared causal variant rs12688220 may modify ACP and NACP risk by increasing CLDN2 expression. |
Diagnosis and treatment of exocrine pancreatic insufficiency in chronic pancreatitis: An international expert survey and case vignette study. This survey identified a lack of consensus and substantial practice variation among international pancreatologists regarding guidelines pertaining the management of exocrine pancreatic insufficiency. These results highlight the need for further adaptation of these guidelines according to current expert opinion and the level of available scientific evidence. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Am J Clin Nutr |
| Liver Transpl |
Letters to the editors and authors’ replies
| Liver Transpl |
all remaining publications eg case reports, images of the month, etc…
| Am J Clin Nutr |